The Human Brain in Ancient Egypt provides a medical and historical re-evaluation of the function and importance of the human brain in ancient Egypt. The study evaluates whether treatment of the brain during anthropogenic mummification was linked to medical concepts of the brain. The notion that excerebration was carried out to rid the body of the brain continues to dominate the literature, and the assumption that the functions of the brain were assigned to the heart and therefore the brain was not needed in the afterlife persists. To assess the validity of these claims the study combines three investigations: a radiological survey of 33 subjects using the IMPACT mummy database to determine treatment of the cranium; an examination of the medical papyri for references to the human brain; and an inspection of the palaeopathological records to look for evidence of cranial injuries and ensuing medical treatments. The results refute long held claims regarding the importance of the human brain in ancient Egypt. Many accepted facets of mummification can no longer hold up to scrutiny. Mummification served a religious ideology in which the deceased was transformed and preserved for eternity. Treatment of the brain was not determined to be significantly different from the visceral organs, and the notion that the brain was extracted because it served no purpose in the afterlife was found to be unsubstantiated.