Dr. Jijun Xu is a physician-scientist practicing at Cleveland Clinic, Ohio, USA. He is an Associate Professor of Anesthesiology and has joint appointments in the Department of Pain Management and Inflammation and Immunity at Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. His basic and clinical training and research experience have inspired him to investigate pain mechanisms and translate research findings into clinical practice. He employs multidisciplinary approaches to treat a variety of chronic pain conditions and his research has been funded by the NIH and numerous professional organizations. Dr. Lynn R. Webster is one of the nation's leading researchers and experts in pain and addiction medicine. His research has spanned 40 years that includes developing novel pharmacologic and interventional therapies. Dr. Webster has been investigator or co-investigator for more than 400 clinical trials and has authored more than 300 publications. He is an educator and an advocate of safe therapies for people with pain and substance use disorders. Dr. Webster was also a co-producer of the critically acclaimed television documentary, "The Painful Truth," which was distributed on national public television.