The year is 1932 on the south side of Chicago. By day, small-time thugs lurk in the shadows, hoping for a big score. By night, criminals hunt unsuspecting victims in a relentless war for power. After the city is freed from the grip of Big Boy Caprice, a new crime boss named Ominous emerges from hiding with his crew. He discovers that a local nightclub holds the darkest secrets necessary to elevate him to the top. When multiple men are gunned down in a warehouse, Dick Tracy and his ambitious partner, Joe Buzzer, take on the case. They follow clues and gather leads throughout the city, while Ominous uses his henchmen-Clover, Torpedo, Jersey, Pinstripe, and Spats-to keep them busy. Tracy and Buzzer must work late into the night if they hope to catch their quarry.